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  • Necrotizing Scleritis and Rheumatoid Arthritis: A Clinical Case Report Supported by a Brief Review With Risk of Bias Analysis
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Necrotizing Scleritis and Rheumatoid Arthritis: A Clinical Case Report Supported by a Brief Review With Risk of Bias Analysis

Publicado por MetaScience Press em 24 de fevereiro de 2023
Categorias
  • Scientific Research
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  • academic article
  • academic articles
  • scientific article
  • scientific articles

Necrotizing scleritis (NS) presents 30%-40% as having a systemic autoimmune condition.

Objective: To present a clinical case report and a systematic review of necrotizing scleritis with ocular manifestation as the first sign of rheumatologic disease.

Methods: The present study was elaborated according to the rules of CARE.

Case report: A female patient, 63 years old, a white, administrative assistant, presented irritation, low visual acuity (LVA) in the left eye (LE), and headache. Biomicroscopy (BIO) in the right eye (RE) was normal, and the LE showed hyperemia and scleral thinning. After 1 month, the patient returns without signs of infectious diseases in the exams, and after a rheumatological evaluation with a diagnosis of rheumatoid arthritis, methotrexate and prednisone are prescribed. After 2 months, she relapsed and started treatment with anti-TNF, with remission after the 4th dose. After 1 year, she evolved with LVA in LE.

Results: A total of 244 articles were found, 104 articles were evaluated and 10 were included in the brief review. The symmetrical Funnel Plot does not suggest a risk of bias.

Conclusion: Both in the present case report and the literary findings, it was evidenced that the ophthalmologic findings may precede the systemic changes of the disease for the early diagnosis of rheumatoid arthritis.

Keywords: Autoimmune diseases; Necrotizing scleritis; Rheumatoid arthritis; Rheumatological diseases; Scleritis.

Source: https://pubmed.ncbi.nlm.nih.gov/36809968/

Source: https://www.eurekaselect.com/article/129682

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    Aluna e docentes do curso de Medicina da UNIFEV publicam artigo em revista científica internacional
    9 de março de 2023
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    Necrotizing Scleritis and Rheumatoid Arthritis: A Clinical Case Report Supported by a Brief Review With Risk of Bias Analysis
    24 de fevereiro de 2023
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    Meta-analysis of the Major Clinical Results of the Treatment with 1-Point Fixation in Fractures in the Zygomatic-Maxillary Complex: Success Rate and Complications
    30 de janeiro de 2023
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